Bio 216 Sp2024: presentation of viral antigens
Bio 216 Sp2024: presentation of viral antigens
Steps involved in this process:
1. Virus infects the cell
2. Viral antigens are packaged into MHC I and presented on the cell surface
3. CD8 cell recognizes the viral antigen (using T-cell receptor) and the MHC I (using its CD8 molecule)
4. CD8 cell releases granzymes and perforin
5. Perforin makes pores in the infected cell membrane, and granzymes enter the infected cell. The cell is destroyed through cell apoptosis and lysis.
-
From Hannah Reynolds
1 plays 0A virus infects a cell. The viral antigens are processed and presented in the MHC class I. A CD8 cell recognizes the antigen/MHC I complex and releases granzymes and… -
From Hannah Reynolds
0 plays 0A cytotoxic T cell (right) interacts with an infected cell (left). The Tc cell releases granzymes and perforins that cause lysis of the target cell. -
From Hannah Reynolds
0 plays 0A virus infects a cell. The viral antigens (green) are processed and presented in the MHC class I (red). A cytotoxic T cell recognizes the antigen/MHC I complex using… -
From Hannah Reynolds
1 plays 0Virus (purple) infects a host cell (bottom). Then the viral antigens are processed, presented in the MHCI, and recognized by a Tc cell using its T-cell receptor and CD8… -
From Hannah Reynolds
0 plays 0Viral antigens (green) are packaged in the MHC class I and processed by the Golgi apparatus. The antigen/MHC I complex travels to the cell membrane of the…